Apcalis Oral Jelly consists of Tadalafil hydrochloride which acts as an active ingredient. Tadalafil belongs to the group of Phosphodisterase type-5 (PDE-5) inhibitors. Apcalis oral jelly is very popular and hugely used by the patient suffering from ED or erectile dysfunction. Jelly form of Apcalis is available in many flavours like banana, strawberry, mint, chocolate etc. This is taken by oral route of administration that should be placed under the tongue where it gets dissolved and then it is swallowed. The advantage of this jelly form of ED medication is that it works fast compared to the tablet form. Always use this medication half-n-hour prior to physical intercourse to have the best result. When this medication is taken, Tadalafil starts acting within 30-45 minutes of after the intake. It inhibits the formation of enzyme PDE type-5 and increases the production of cGMP. The higher cGMP will increase the blood flow to the male genital area under the influence of nitric oxide present in the spongy tissue called corpus covernosum present in the penis. Thus it improves the erection. Apcalis is approved by FDA in 2003 for the treatment of ED. Tadalafil was approved by FDA in 2003. It is a long-acting medication whose effect lasts for 36 hours.
What are the uses?
Apcalis contains a Phosphodiesterase type–5 inhibitor which is used for the treatment of:
1. Erectile dysfunction in males
2. Benign prostate hyperplasia (BPH)
How does it work?
Apcalis oral jelly or Tadalafil inhibits the formation of enzyme PDE type-5 and increases the production of cGMP. The higher cGMP will increase the blood flow to the male genital area under the influence of nitric oxide present in the spongy tissue called corpus covernosum present in the penis. Thus it improves the erection. But this ED medication functions only in the presence of sexual stimulation. Sexual stimulation stimulates the release of nitric oxide which is the key factor of the erection. So always take Apcalis oral jelly in planned intercourse.
What is the indication of Apcalis Oral Jelly?
This medication is indicated for the treatment of erectile dysfunction and benign prostatic hyperplasia.
What is the dose?
Apcalis oral jelly is available at the strengths of 5mg, 10mg and 20mg. The recommended dose is 10mg. But depending on the requirement and tolerability, the dosage can be decreased to 5mg or 10mg. But you should always let your doctor to decide the actual dose suited for you. Since its duration of action is longer (36 hours), so its time of intake will be differ from other ED medication. So consult with your doctor regarding the time of intake.
What are the side effects?
All the patients using this medication do not face the side effects. According to the study, only 1-2% people catch side effects of this medication. The common side effects are headache, nausea, facial flushing, Diarrhoea, flu like symptoms etc.
Serious but rare side effects:
1. Allergic reaction like rash, itching, redness, swelling of lips, throat, eyelids
2. Dizziness, drowsiness
3. Chest pain, palpitation, Increased heart rate
4. Blurred vision or sudden vision loss in one or both eyes
5. Ringing in the ear or sudden hearing loss
6. Pain in arm/legs, muscle pain
7. Nasal congestion
8. Low blood pressure
What are the contraindications?
1. Patients who are allergic to Tadalafil or any ingredient of this medication.
2. Children under 18 years.
3. Patients who are taking nitrates or recreational medicines.
What are precautions?
1. Do not take this medication if you are experiencing Peyronie’s disease, fibrosis, leukaemia, myeloma sickle cell anaemia, or retinitis pigmentosa.
2. Avoid if you have heart disease or other serious health issue.
3. Alcohol consumption should be ceased during the use of this medication.
4. Avoid any activities which require mental alertness after taking Apcalis oral jelly because this medication can make you feel dizziness, drosiness, blurred vision etc.
5. If you catch vision problem, ear problem then discontinue this medication and talk to your doctor immediately.
Which are the drug interactions?
Some of the drug interactions of this medication are:
1. Phenobarbitone, Carbamazepine, Rifampin and Phenytoin.
2. Erythromycin, Ketoconazole, Indinavir, Ritonavir, and Itraconazole.
3. Medications used in Cardiac diseases.
4. Medications containing nitrates and nitrites.
What should be the storage conditions?
The medicine should be stored at room temperature that is below 30 degree C. It should be kept away from children and domestic pets, in a dry place, protecting from heat and light.